The Canadian AI Index

Companies / Congruence Therapeutics

Congruence Therapeutics

Congruence Therapeutics is a health and biotech AI company based in Montréal, Quebec. It had raised US$71.5M as of November 2026, most recently a US$39.5M venture round in March 2026 led by Dimension and OrbiMed.

Computationally driven drug discovery using its Revenir platform (biophysics and machine learning) to design small-molecule correctors for protein-misfolding diseases.

congruencetx.com

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Founded
2021
HQ
Montréal, QC
Category
Health/Bio AI
Status
Active
Disclosed raised
US$71.5M

Funding history

RoundDateAmountInvestors
Venture roundMar 19, 2026 US$39.5MDimension and OrbiMed (co-leads); Amplitude Ventures, Fonds de solidarité FTQ, Lumira Ventures, Investissement Québec, BDC Thrive Venture Fund, Driehaus Capital Management, Silver Arc Capital. Co-led by Dimension (new) and OrbiMed; Amplitude Ventures, FSTQ, Lumira, Investissement Québec, BDC Thrive Venture Fund, Driehaus and Silver Arc participated
Venture roundSep 4, 2025 US$32MAmplitude Ventures, Fonds de solidarité FTQ, Lumira Ventures, Investissement Québec, BDC Thrive Venture Fund, OrbiMed, Driehaus Capital Management, Silver Arc Capital, Alexandria Venture Investments. Insider round from existing investors (Amplitude Ventures, Fonds de solidarité FTQ, Lumira Ventures, Investissement Québec, BDC Thrive Venture Fund, OrbiMed, Driehaus, Silver Arc, Alexandria) to fund the CGX-926 Phase 1. Announcement date per BioWorld Sep 5 2025 coverage, to confirm

Founders

Sources

Data as of November 10, 2026.

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